Details:

Post-Golgi LH3 trafficking pathway. LH3, VIPAR and VPS33B containing vesicle buds at TGN (step 1) with membrane-associated RAB10 (steps 1 and 2) and -RAB25 (step 3). LH3 containing vesicle fuses with collagen IV carrier (step 4). VIPAR and VPS33B independent LH3 transport to CD63 positive organelles (step 1a).
Banushi B, Forneris F, Straatman-Iwanowska A, Strange A, Lyne A M, Rogerson C, Burden J J, Heywood W E, Hanley J, Doykov I, Straatman K R, Smith H, Bem D, Kriston-Vizi J, Ariceta G, Risteli M, Wang C, Ardill RE, Zaniew M, Latka-Grot J, Waddington S N, Howe S J, Ferraro F, Gjinovci A, Lawrence S, Marsh M, Girolami M, Bozec L, Mills K, Gissen P. Nat Commun. 7-2016.

go to article

Our Involvement:

• Year: 2016
• Client: UCL - MRC Laboratory for Molecular Cell Biology - Prof.Paul Gissen
• Services: 3D illustration